CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis

BACKGROUND: The poor prognosis of esophageal squamous cell carcinoma (ESCC) highlights the need for novel strategies against this disease. Our previous study suggested the involvement of CCL2 and tumor associated macrophages (TAMs) in esophageal carcinogenesis. Despite the recognition of TAMs as a p...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Zhang, Qiannan, Xu, Miao, Wang, Lei, Chen, Xuewei, Feng, Yongquan, Li, Yongning, Zhang, Xin, Cui, Wenming, Jia, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045401/
https://www.ncbi.nlm.nih.gov/pubmed/32103760
http://dx.doi.org/10.1186/s12943-020-01165-x

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