Insulin-like growth factor-II overexpression accelerates parthenogenetic stem cell differentiation into cardiomyocytes and improves cardiac function after acute myocardial infarction in mice

BACKGROUND: Parthenogenetic stem cells (PSCs) are a promising source of regenerated cardiomyocytes; however, their application may be limited without a paternal genome. Insulin-like growth factor-II (IGF-II), a paternally expressed growth hormone, is critical in embryonic differentiation. This study...

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Detalles Bibliográficos
Autores principales: Sui, Yi, Zhang, Wei, Tang, Tao, Gao, Lili, Cao, Ting, Zhu, Hongbo, You, Qinghua, Yu, Bo, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045450/
https://www.ncbi.nlm.nih.gov/pubmed/32102690
http://dx.doi.org/10.1186/s13287-020-1575-4

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