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Estimating linkage disequilibrium from genotypes under Hardy-Weinberg equilibrium
BACKGROUND: Measures of linkage disequilibrium (LD) play a key role in a wide range of applications from disease association to demographic history estimation. The true population LD cannot be measured directly and instead can only be inferred from genetic samples, which are unavoidably subject to m...
Autores principales: | Hui, Tin-Yu J., Burt, Austin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045472/ https://www.ncbi.nlm.nih.gov/pubmed/32102657 http://dx.doi.org/10.1186/s12863-020-0818-9 |
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