Cargando…

Exosomal microRNA-144 from bone marrow-derived mesenchymal stem cells inhibits the progression of non-small cell lung cancer by targeting CCNE1 and CCNE2

BACKGROUND: Mesenchymal stem cells (MSCs) are pluripotent mesenchymal cells present in various adult tissues. MSCs secrete exosomes as regulators of the tumor niche, with involvement in tumorigenesis and metastasis. The regulatory role of microRNAs (miRs or miRNAs) in MSCs via targeting cyclin E1 (C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Yuan, Zhang, Dalin, Li, Linlin, Xin, Tian, Zhao, Yuwei, Ma, Rui, Du, Jiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045474/ https://www.ncbi.nlm.nih.gov/pubmed/32102682 http://dx.doi.org/10.1186/s13287-020-1580-7

Ejemplares similares

Tumour-suppressive microRNA-144-5p directly targets CCNE1/2 as potential prognostic markers in bladder cancer
por: Matsushita, R, et al.
Publicado: (2015)

Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo
por: Cocco, Emiliano, et al.
Publicado: (2016)

microRNA-25 Inhibits Cell Apoptosis of Human Gastric Adenocarcinoma Cell Line AGS via Regulating CCNE1 and MYC
por: Zhang, Yong, et al.
Publicado: (2016)

CCNE1 amplification is associated with aggressive potential in endometrioid endometrial carcinomas
por: NAKAYAMA, KENTARO, et al.
Publicado: (2015)

CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
por: Gallo, David, et al.
Publicado: (2022)

CARM1 promotes non-small cell lung cancer progression through upregulating CCNE2 expression
por: Wu, Deqin, et al.
Publicado: (2020)

CCNE1 expression in high grade serous carcinoma does not correlate with chemoresistance
por: Sapoznik, Stav, et al.
Publicado: (2017)

Down-regulation of CCNE1 expression suppresses cell proliferation and sensitizes gastric carcinoma cells to Cisplatin
por: Zhang, Chao, et al.
Publicado: (2019)

ALDH Maintains the Stemness of Lung Adenoma Stem Cells by Suppressing the Notch/CDK2/CCNE Pathway
por: Li, Zhongjun, et al.
Publicado: (2014)

CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer
por: Zhao, Zi-Ming, et al.
Publicado: (2019)

CCNE1 Amplification as a Predictive Biomarker of Chemotherapy Resistance in Epithelial Ovarian Cancer
por: Gorski, Justin W., et al.
Publicado: (2020)

ZYG11A serves as an oncogene in non-small cell lung cancer and influences CCNE1 expression
por: Wang, Xin, et al.
Publicado: (2016)

CCNE1 Is a Putative Therapeutic Target for ARID1A-Mutated Ovarian Clear Cell Carcinoma
por: Kawahara, Naoki, et al.
Publicado: (2021)

Functional exploration of CCNE1 splicing forms as a possible link to bladder cancer susceptibility
por: Kohaar, Indu, et al.
Publicado: (2011)

A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness
por: Pegoraro, Silvia, et al.
Publicado: (2015)

AB267. Association of genetic polymorphism of CCNE1 and RIP2 with bladder cancer risk
por: Liang, Enli
Publicado: (2016)

CCNE1 amplification among metastatic sites in patients with gynecologic high-grade serous carcinoma
por: Margolis, Benjamin, et al.
Publicado: (2021)

Bone marrow mesenchymal stem cell-derived exosomal microRNA regulates microglial polarization
por: Huang, Xianwei, et al.
Publicado: (2023)

Circular RNA CircCCNB1 sponges micro RNA-449a to inhibit cellular senescence by targeting CCNE2
por: Yu, Ai Qing, et al.
Publicado: (2019)

Antibiotic tigecycline inhibits cell proliferation, migration and invasion via down‐regulating CCNE2 in pancreatic ductal adenocarcinoma
por: Yang, Jie, et al.
Publicado: (2020)

Association of Germline Variation in CCNE1 and CDK2 with Breast Cancer Risk, Progression and Survival among Chinese Han Women
por: Han, Ji-Yuan, et al.
Publicado: (2012)

Prognostic Values of CCNE1 Amplification and Overexpression in Cancer Patients: A Systematic Review and Meta-analysis
por: Zhao, Haiyue, et al.
Publicado: (2018)

Multiple bronchiolar adenomas with malignant transformation and CCNE1 mutation: a case report and literature review
por: Li, Xiaojun, et al.
Publicado: (2021)

KDM5B promotes tumorigenesis of Ewing sarcoma via FBXW7/CCNE1 axis
por: Chen, Binbin, et al.
Publicado: (2022)

Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences
por: Yao, Shuyang, et al.
Publicado: (2022)

CCNE1 and PLK1 Mediate Resistance to Palbociclib in HR+/HER2− Metastatic Breast Cancer
por: Guerrero-Zotano, Ángel, et al.
Publicado: (2023)

Circular RNA circ-CSPP1 regulates CCNE2 to facilitate hepatocellular carcinoma cell growth via sponging miR-577
por: Sun, Qian, et al.
Publicado: (2020)

SUN-646 A Novel Population of FOXO1-Expressing Cells in the Stomach Controls Cell Plasticity by Regulating the Cyclin CCNE1
por: McKimpson, Wendy M, et al.
Publicado: (2020)

CDK2 regulates collapsed replication fork repair in CCNE1-amplified ovarian cancer cells via homologous recombination
por: Brown, Victoria E, et al.
Publicado: (2023)

CBX7 is a glioma prognostic marker and induces G1/S arrest via the silencing of CCNE1
por: Yu, Tianfu, et al.
Publicado: (2017)

Overexpression of CCNE1 confers a poorer prognosis in triple-negative breast cancer identified by bioinformatic analysis
por: Yuan, Qianqian, et al.
Publicado: (2021)

Knockdown of SENP1 inhibits HIF-1α SUMOylation and suppresses oncogenic CCNE1 in Wilms tumor
por: Zhu, Shibo, et al.
Publicado: (2021)

Carbapenemase-Encoding Gene Copy Number Estimator (CCNE): a Tool for Carbapenemase Gene Copy Number Estimation
por: Jiang, Jianping, et al.
Publicado: (2022)

CCNE1 is a predictive and immunotherapeutic indicator in various cancers including UCEC: a pan-cancer analysis
por: Zheng, Xingyu, et al.
Publicado: (2023)

Correction to: Circular RNA circ-CSPP1 regulates CCNE2 to facilitate hepatocellular carcinoma cell growth via sponging miR-577
por: Sun, Qian, et al.
Publicado: (2020)

CircDENND2A Promotes Non-small Cell Lung Cancer Progression via Regulating MiR-34a/CCNE1 Signaling
por: Zhang, Yinbin, et al.
Publicado: (2020)

miR-3607-3p suppresses non-small cell lung cancer (NSCLC) by targeting TGFBR1 and CCNE2
por: Gao, Peng, et al.
Publicado: (2018)

CCNE1 and BRD4 co-amplification in high-grade serous ovarian cancer is associated with poor clinical outcomes
por: Petersen, Shariska, et al.
Publicado: (2020)

Retraction Note: circular RNA circ-CSPP1 regulates CCNE2 to facilitate hepatocellular carcinoma cell growth via sponging miR-577
por: Sun, Qian, et al.
Publicado: (2023)

MicroRNAs of bone marrow mesenchymal stem cell-derived exosomes regulate acute myeloid leukemia cell proliferation and apoptosis
por: Xu, Yi-Chuan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_l1uq8arq0vb8moog0ojq7kqct5