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A rare codon-based translational program of cell proliferation
BACKGROUND: The speed of translation elongation is primarily determined by the abundance of tRNAs. Thus, the codon usage influences the rate with which individual mRNAs are translated. As the nature of tRNA pools and modifications can vary across biological conditions, codon elongation rates may als...
Autores principales: | Guimaraes, Joao C., Mittal, Nitish, Gnann, Alexandra, Jedlinski, Dominik, Riba, Andrea, Buczak, Katarzyna, Schmidt, Alexander, Zavolan, Mihaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045563/ https://www.ncbi.nlm.nih.gov/pubmed/32102681 http://dx.doi.org/10.1186/s13059-020-1943-5 |
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