X-ray computed tomography in life sciences

Recent developments within micro-computed tomography (μCT) imaging have combined to extend our capacity to image tissue in three (3D) and four (4D) dimensions at micron and sub-micron spatial resolutions, opening the way for virtual histology, live cell imaging, subcellular imaging and correlative m...

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Autores principales: Rawson, Shelley D., Maksimcuka, Jekaterina, Withers, Philip J., Cartmell, Sarah H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045626/
https://www.ncbi.nlm.nih.gov/pubmed/32103752
http://dx.doi.org/10.1186/s12915-020-0753-2
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author Rawson, Shelley D.
Maksimcuka, Jekaterina
Withers, Philip J.
Cartmell, Sarah H.
author_facet Rawson, Shelley D.
Maksimcuka, Jekaterina
Withers, Philip J.
Cartmell, Sarah H.
author_sort Rawson, Shelley D.
collection PubMed
description Recent developments within micro-computed tomography (μCT) imaging have combined to extend our capacity to image tissue in three (3D) and four (4D) dimensions at micron and sub-micron spatial resolutions, opening the way for virtual histology, live cell imaging, subcellular imaging and correlative microscopy. Pivotal to this has been the development of methods to extend the contrast achievable for soft tissue. Herein, we review the new capabilities within the field of life sciences imaging, and consider how future developments in this field could further benefit the life sciences community.
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spelling pubmed-70456262020-03-03 X-ray computed tomography in life sciences Rawson, Shelley D. Maksimcuka, Jekaterina Withers, Philip J. Cartmell, Sarah H. BMC Biol Review Recent developments within micro-computed tomography (μCT) imaging have combined to extend our capacity to image tissue in three (3D) and four (4D) dimensions at micron and sub-micron spatial resolutions, opening the way for virtual histology, live cell imaging, subcellular imaging and correlative microscopy. Pivotal to this has been the development of methods to extend the contrast achievable for soft tissue. Herein, we review the new capabilities within the field of life sciences imaging, and consider how future developments in this field could further benefit the life sciences community. BioMed Central 2020-02-27 /pmc/articles/PMC7045626/ /pubmed/32103752 http://dx.doi.org/10.1186/s12915-020-0753-2 Text en © The Author(s). 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Rawson, Shelley D.
Maksimcuka, Jekaterina
Withers, Philip J.
Cartmell, Sarah H.
X-ray computed tomography in life sciences
title X-ray computed tomography in life sciences
title_full X-ray computed tomography in life sciences
title_fullStr X-ray computed tomography in life sciences
title_full_unstemmed X-ray computed tomography in life sciences
title_short X-ray computed tomography in life sciences
title_sort x-ray computed tomography in life sciences
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045626/
https://www.ncbi.nlm.nih.gov/pubmed/32103752
http://dx.doi.org/10.1186/s12915-020-0753-2
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AT cartmellsarahh xraycomputedtomographyinlifesciences

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