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Chemoenzymatic Halocyclization of 4-Pentenoic Acid at Preparative Scale
[Image: see text] The scale-up of chemoenzymatic bromolactonization to 100 g scale is presented, together with an identification of current limitations. The preparative-scale reaction also allowed for meaningful mass balances identifying current bottlenecks of the chemoenzymatic reaction.
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045808/ https://www.ncbi.nlm.nih.gov/pubmed/32117647 http://dx.doi.org/10.1021/acssuschemeng.9b07494 |