Chemoenzymatic Halocyclization of 4-Pentenoic Acid at Preparative Scale

[Image: see text] The scale-up of chemoenzymatic bromolactonization to 100 g scale is presented, together with an identification of current limitations. The preparative-scale reaction also allowed for meaningful mass balances identifying current bottlenecks of the chemoenzymatic reaction.

Detalles Bibliográficos
Autores principales: Höfler, Georg T., But, Andrada, Younes, Sabry H. H., Wever, Ron, Paul, Caroline E., Arends, Isabel W. C. E., Hollmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045808/
https://www.ncbi.nlm.nih.gov/pubmed/32117647
http://dx.doi.org/10.1021/acssuschemeng.9b07494

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