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Interferon targeted therapies in systemic lupus erythematosus

Type I interferons secreted by plasmacytoid dendritic cells (pDCs) play a crucial role in the pathogenesis of systemic lupus erythematosus by driving the formation of autoantibodies against nuclear debris. Inherited mutations causing activation of the Type I interferon pathway result in a phenotype...

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Detalles Bibliográficos
Autores principales:	Misra, Durga Prasanna, Negi, Vir Singh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Mediterranean Journal of Rheumatology (MJR) 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045923/ https://www.ncbi.nlm.nih.gov/pubmed/32185249 http://dx.doi.org/10.31138/mjr.28.1.13

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