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68-year old woman with refractory cutaneous dermatomyositis
Dermatomyositis is an idiopathic inflammatory disorder of the muscles associated with characteristic cutaneous findings. Herein we report a 68-year old woman who presented with dermatomyositis associated with painful vasculitic lesions on both hands, refractory to conventional treatment. Steroids, t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Mediterranean Journal of Rheumatology (MJR)
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045944/ https://www.ncbi.nlm.nih.gov/pubmed/32185331 http://dx.doi.org/10.31138/mjr.29.4.221 |
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author | Antonopoulos, Ioannis Liossis, Stamatis-Nick |
author_facet | Antonopoulos, Ioannis Liossis, Stamatis-Nick |
author_sort | Antonopoulos, Ioannis |
collection | PubMed |
description | Dermatomyositis is an idiopathic inflammatory disorder of the muscles associated with characteristic cutaneous findings. Herein we report a 68-year old woman who presented with dermatomyositis associated with painful vasculitic lesions on both hands, refractory to conventional treatment. Steroids, topical tacrolimus, antimalarials and intravenous cyclophosphamide were tried with no beneficial effect. Rituximab was also administered with no initial effect; soon afterwards, intravenous immunoglobulin was administered with good results. Some cases of cutaneous dermatomyositis may require trials of different therapies to identify the treatment regimen that produces satisfactory disease control. |
format | Online Article Text |
id | pubmed-7045944 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Mediterranean Journal of Rheumatology (MJR) |
record_format | MEDLINE/PubMed |
spelling | pubmed-70459442020-03-17 68-year old woman with refractory cutaneous dermatomyositis Antonopoulos, Ioannis Liossis, Stamatis-Nick Mediterr J Rheumatol Case Report Dermatomyositis is an idiopathic inflammatory disorder of the muscles associated with characteristic cutaneous findings. Herein we report a 68-year old woman who presented with dermatomyositis associated with painful vasculitic lesions on both hands, refractory to conventional treatment. Steroids, topical tacrolimus, antimalarials and intravenous cyclophosphamide were tried with no beneficial effect. Rituximab was also administered with no initial effect; soon afterwards, intravenous immunoglobulin was administered with good results. Some cases of cutaneous dermatomyositis may require trials of different therapies to identify the treatment regimen that produces satisfactory disease control. The Mediterranean Journal of Rheumatology (MJR) 2018-12-18 /pmc/articles/PMC7045944/ /pubmed/32185331 http://dx.doi.org/10.31138/mjr.29.4.221 Text en © 2018 The Mediterranean Journal of Rheumatology (MJR) http://creativecommons.org/licenses/by/4.0/ This work is licensed under and Creative Commons Attribution-NonCommercial 4.0 International License. |
spellingShingle | Case Report Antonopoulos, Ioannis Liossis, Stamatis-Nick 68-year old woman with refractory cutaneous dermatomyositis |
title | 68-year old woman with refractory cutaneous dermatomyositis |
title_full | 68-year old woman with refractory cutaneous dermatomyositis |
title_fullStr | 68-year old woman with refractory cutaneous dermatomyositis |
title_full_unstemmed | 68-year old woman with refractory cutaneous dermatomyositis |
title_short | 68-year old woman with refractory cutaneous dermatomyositis |
title_sort | 68-year old woman with refractory cutaneous dermatomyositis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045944/ https://www.ncbi.nlm.nih.gov/pubmed/32185331 http://dx.doi.org/10.31138/mjr.29.4.221 |
work_keys_str_mv | AT antonopoulosioannis 68yearoldwomanwithrefractorycutaneousdermatomyositis AT liossisstamatisnick 68yearoldwomanwithrefractorycutaneousdermatomyositis |