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The effect of Apremilast on signal transduction and IL-10 production in CD39high regulatory B cells in patients with psoriatic arthritis

BACKGROUND. IL-10-producing regulatory B cells (Bregs) are of great importance in autoimmunity, as they inhibit proinflammatory T cells. We have shown that IL-10-producing Bregs in psoriatic arthritis(PsA) were decreased and inversely correlated with IFNγ+T cells (TH1 cells) and IL-17+ T cells (TH17...

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Detalles Bibliográficos
Autores principales:	Sakkas, Lazaros I., Mavropoulos, Athanasios, Zafiriou, Efterpi, Roussaki-Schulze, Aggeliki, Bogdanos, Dimitrios P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Mediterranean Journal of Rheumatology (MJR) 2018
Materias:	Research Protocols-Proposals
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045954/ https://www.ncbi.nlm.nih.gov/pubmed/32185301 http://dx.doi.org/10.31138/mjr.29.1.59

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