Cargando…

Conversion from Off to On-Pump Coronary Artery Bypass Grafting. Is it Avoidable?

Background With the emergence of new technologies to stabilize the heart off-pump coronary artery bypass grafting (OPCAB), there is an increasing trend that is being observed throughout the world. In certain circumstances, OPCAB needs to be converted to on-pump CABG (ONCAB). In this study, we aim to...

Descripción completa

Detalles Bibliográficos
Autores principales: Tariq, Khuzaima, Zia, Kashif, Mangi, Ali, Amanullah, Muneer, Chaudry, Pervaiz A, Karim, Musa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046009/
https://www.ncbi.nlm.nih.gov/pubmed/32140350
http://dx.doi.org/10.7759/cureus.6791
_version_ 1783501888525697024
author Tariq, Khuzaima
Zia, Kashif
Mangi, Ali
Amanullah, Muneer
Chaudry, Pervaiz A
Karim, Musa
author_facet Tariq, Khuzaima
Zia, Kashif
Mangi, Ali
Amanullah, Muneer
Chaudry, Pervaiz A
Karim, Musa
author_sort Tariq, Khuzaima
collection PubMed
description Background With the emergence of new technologies to stabilize the heart off-pump coronary artery bypass grafting (OPCAB), there is an increasing trend that is being observed throughout the world. In certain circumstances, OPCAB needs to be converted to on-pump CABG (ONCAB). In this study, we aim to identify certain risk factors mandating conversions and their associated short-term outcomes. Methods After approval from the institutional ethical review committee and exemption from informed consent, retrospective data of 100 patients meeting the inclusion criteria who underwent OPCAB operations at our institution from August 2018 to July 2019 were included. Preoperative, intraoperative, and postoperative variables were recorded and compared in conversion and non-conversion groups. This study was conducted at the National Institute of Cardiovascular Diseases, Karachi, Pakistan. Results A total of 100 patients were included in this study, out of which 82% (82) were male, with age ranging between 18 and 77 years with a mean age of 56.34 ± 8.3 years. In nine of the cases, OPCAB was emergently converted to ONCAB due to arrhythmias. In nine (9%) cases, off-pump CABG was emergently converted to on-pump CABG (ONCAB). Emergent conversion was due to arrhythmias in five cases, due to hypotension during OM graft in two cases, and due to hypotension during ramus graft for the remaining two cases. The emergent conversion was significantly associated with higher New York Heart Association (NYHA) functional classification and comorbid conditions such as chronic obstructive pulmonary disease (COPD). Conclusion Emergency conversion from off-pump to OPCAB is the most catastrophic event causing higher morbidity and mortality. Conversion rate was observed to be 9% with arrhythmias being the common cause and patients with higher NYHA status and COPD at baseline were found to be at increased risk of emergency conversion. Considering our results in patients with diagnosed COPD and higher NYHA status, the decision for off-pump CABG should be wisely taken carefully weighing the risks and benefits.
format Online
Article
Text
id pubmed-7046009
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-70460092020-03-05 Conversion from Off to On-Pump Coronary Artery Bypass Grafting. Is it Avoidable? Tariq, Khuzaima Zia, Kashif Mangi, Ali Amanullah, Muneer Chaudry, Pervaiz A Karim, Musa Cureus Cardiac/Thoracic/Vascular Surgery Background With the emergence of new technologies to stabilize the heart off-pump coronary artery bypass grafting (OPCAB), there is an increasing trend that is being observed throughout the world. In certain circumstances, OPCAB needs to be converted to on-pump CABG (ONCAB). In this study, we aim to identify certain risk factors mandating conversions and their associated short-term outcomes. Methods After approval from the institutional ethical review committee and exemption from informed consent, retrospective data of 100 patients meeting the inclusion criteria who underwent OPCAB operations at our institution from August 2018 to July 2019 were included. Preoperative, intraoperative, and postoperative variables were recorded and compared in conversion and non-conversion groups. This study was conducted at the National Institute of Cardiovascular Diseases, Karachi, Pakistan. Results A total of 100 patients were included in this study, out of which 82% (82) were male, with age ranging between 18 and 77 years with a mean age of 56.34 ± 8.3 years. In nine of the cases, OPCAB was emergently converted to ONCAB due to arrhythmias. In nine (9%) cases, off-pump CABG was emergently converted to on-pump CABG (ONCAB). Emergent conversion was due to arrhythmias in five cases, due to hypotension during OM graft in two cases, and due to hypotension during ramus graft for the remaining two cases. The emergent conversion was significantly associated with higher New York Heart Association (NYHA) functional classification and comorbid conditions such as chronic obstructive pulmonary disease (COPD). Conclusion Emergency conversion from off-pump to OPCAB is the most catastrophic event causing higher morbidity and mortality. Conversion rate was observed to be 9% with arrhythmias being the common cause and patients with higher NYHA status and COPD at baseline were found to be at increased risk of emergency conversion. Considering our results in patients with diagnosed COPD and higher NYHA status, the decision for off-pump CABG should be wisely taken carefully weighing the risks and benefits. Cureus 2020-01-27 /pmc/articles/PMC7046009/ /pubmed/32140350 http://dx.doi.org/10.7759/cureus.6791 Text en Copyright © 2020, Tariq et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiac/Thoracic/Vascular Surgery
Tariq, Khuzaima
Zia, Kashif
Mangi, Ali
Amanullah, Muneer
Chaudry, Pervaiz A
Karim, Musa
Conversion from Off to On-Pump Coronary Artery Bypass Grafting. Is it Avoidable?
title Conversion from Off to On-Pump Coronary Artery Bypass Grafting. Is it Avoidable?
title_full Conversion from Off to On-Pump Coronary Artery Bypass Grafting. Is it Avoidable?
title_fullStr Conversion from Off to On-Pump Coronary Artery Bypass Grafting. Is it Avoidable?
title_full_unstemmed Conversion from Off to On-Pump Coronary Artery Bypass Grafting. Is it Avoidable?
title_short Conversion from Off to On-Pump Coronary Artery Bypass Grafting. Is it Avoidable?
title_sort conversion from off to on-pump coronary artery bypass grafting. is it avoidable?
topic Cardiac/Thoracic/Vascular Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046009/
https://www.ncbi.nlm.nih.gov/pubmed/32140350
http://dx.doi.org/10.7759/cureus.6791
work_keys_str_mv AT tariqkhuzaima conversionfromofftoonpumpcoronaryarterybypassgraftingisitavoidable
AT ziakashif conversionfromofftoonpumpcoronaryarterybypassgraftingisitavoidable
AT mangiali conversionfromofftoonpumpcoronaryarterybypassgraftingisitavoidable
AT amanullahmuneer conversionfromofftoonpumpcoronaryarterybypassgraftingisitavoidable
AT chaudrypervaiza conversionfromofftoonpumpcoronaryarterybypassgraftingisitavoidable
AT karimmusa conversionfromofftoonpumpcoronaryarterybypassgraftingisitavoidable