Targeting tRNA-synthetase interactions towards novel therapeutic discovery against eukaryotic pathogens

The development of chemotherapies against eukaryotic pathogens is especially challenging because of both the evolutionary conservation of drug targets between host and parasite, and the evolution of strain-dependent drug resistance. There is a strong need for new nontoxic drugs with broad-spectrum a...

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Detalles Bibliográficos
Autores principales: Kelly, Paul, Hadi-Nezhad, Fatemeh, Liu, Dennis Y., Lawrence, Travis J., Linington, Roger G., Ibba, Michael, Ardell, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046186/
https://www.ncbi.nlm.nih.gov/pubmed/32106219
http://dx.doi.org/10.1371/journal.pntd.0007983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046186/
https://www.ncbi.nlm.nih.gov/pubmed/32106219
http://dx.doi.org/10.1371/journal.pntd.0007983

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