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Targeting tRNA-synthetase interactions towards novel therapeutic discovery against eukaryotic pathogens
The development of chemotherapies against eukaryotic pathogens is especially challenging because of both the evolutionary conservation of drug targets between host and parasite, and the evolution of strain-dependent drug resistance. There is a strong need for new nontoxic drugs with broad-spectrum a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046186/ https://www.ncbi.nlm.nih.gov/pubmed/32106219 http://dx.doi.org/10.1371/journal.pntd.0007983 |