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Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells
Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in children worldwide. Sirtuin 1 (SIRT1), a NAD+ dependent deacetylase, has been associated with induction of autophagy, reprogramming cellular metabolism, and regulating immune mediators. In this study, we inv...
Autores principales: | Elesela, Srikanth, Morris, Susan B., Narayanan, Samanthi, Kumar, Surinder, Lombard, David B., Lukacs, Nicholas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046194/ https://www.ncbi.nlm.nih.gov/pubmed/32106265 http://dx.doi.org/10.1371/journal.ppat.1008319 |
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