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Interferon-stimulated gene 20 (ISG20) selectively degrades N6-methyladenosine modified Hepatitis B Virus transcripts

Interferon (IFN) stimulates a whole repertoire of cellular genes, collectively referred to as ISGs (Interferon-stimulated genes). ISG20, a 3´-5´ exonuclease enzyme, has been previously shown to bind and degrade hepatitis B Virus (HBV) transcripts. Here, we show that the N6-methyladenosine (m(6)A)-mo...

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Detalles Bibliográficos
Autores principales:	Imam, Hasan, Kim, Geon-Woo, Mir, Saiful Anam, Khan, Mohsin, Siddiqui, Aleem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046284/ https://www.ncbi.nlm.nih.gov/pubmed/32059034 http://dx.doi.org/10.1371/journal.ppat.1008338

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