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SPAG5‐AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway
OBJECTIVES: Podocyte injury is a prediction marker of diabetic nephropathy (DN), and AKT/mTOR pathway–mediated inhibition of autophagy is widely reported to contribute to podocyte damage. Recent study stated that sperm‐associated antigen 5 (SPAG5) activated AKT/mTOR signalling in bladder urothelial...
Autores principales: | Xu, Jun, Deng, Yujie, Wang, Yi, Sun, Xiaofang, Chen, Shuqin, Fu, Guoxiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046304/ https://www.ncbi.nlm.nih.gov/pubmed/31957155 http://dx.doi.org/10.1111/cpr.12738 |
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