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A phenotypic screening platform utilising human spermatozoa identifies compounds with contraceptive activity
There is an urgent need to develop new methods for male contraception, however a major barrier to drug discovery has been the lack of validated targets and the absence of an effective high-throughput phenotypic screening system. To address this deficit, we developed a fully-automated robotic screeni...
Autores principales: | Gruber, Franz S, Johnston, Zoe C, Barratt, Christopher LR, Andrews, Paul D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046468/ https://www.ncbi.nlm.nih.gov/pubmed/31987071 http://dx.doi.org/10.7554/eLife.51739 |
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