Cargando…
Systematic expression analysis of WEE family kinases reveals the importance of PKMYT1 in breast carcinogenesis
OBJECTIVES: Many cancer cells depend on G2 checkpoint mechanism regulated by WEE family kinases to maintain genomic integrity. The PKMYT1 gene, as a member of WEE family kinases, participates in G2 checkpoint surveillance and probably links with tumorigenesis, but its role in breast cancer remains l...
Autores principales: | Liu, Yu, Qi, Jian, Dou, Zhen, Hu, Jiliang, Lu, Li, Dai, Haiming, Wang, Hongzhi, Yang, Wulin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046476/ https://www.ncbi.nlm.nih.gov/pubmed/31837068 http://dx.doi.org/10.1111/cpr.12741 |
Ejemplares similares
-
Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases
por: Schmidt, Matthias, et al.
Publicado: (2017) -
Identification of FPR3 as a Unique Biomarker for Targeted Therapy in the Immune Microenvironment of Breast Cancer
por: Qi, Jian, et al.
Publicado: (2021) -
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
por: Gallo, David, et al.
Publicado: (2022) -
Synthetic lethal interaction between WEE1 and PKMYT1 is a target for multiple low-dose treatment of high-grade serous ovarian carcinoma
por: Benada, Jan, et al.
Publicado: (2023) -
PKMYT1 Promotes Gastric Cancer Cell Proliferation and Apoptosis Resistance
por: Zhang, Qi-Yong, et al.
Publicado: (2020)