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Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy
miR-155 was synthesized and loaded into exosomes in increased infiltration of macrophages in a uremic heart. The released exosomal fusion with the plasma membrane leads to the release of miR-155 into the cytosol and translational repression of forkhead transcription factors of the O class (FoxO3a) i...
Autores principales: | Wang, Bin, Wang, Ze-Mu, Ji, Jia-Ling, Gan, Weihua, Zhang, Aiqing, Shi, Hao-Jie, Wang, Hao, Lv, Linli, Li, Zuolin, Tang, Taotao, Du, Jie, Wang, Xiaonan H., Liu, Bi-Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046511/ https://www.ncbi.nlm.nih.gov/pubmed/32140622 http://dx.doi.org/10.1016/j.jacbts.2019.10.011 |
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