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Genetic Deletion of Socs3 in Smooth Muscle Cells Ameliorates Aortic Dissection in Mice

Aortic dissection (AD) is the acute destruction of aortic wall and is reportedly induced by inflammatory response. Here we investigated the role of smooth muscle Socs3 (a negative regulator of Janus kinases/signal transducer and activator of transcription signaling) in AD pathogenesis using a mouse...

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Detalles Bibliográficos
Autores principales: Hirakata, Saki, Aoki, Hiroki, Ohno-Urabe, Satoko, Nishihara, Michihide, Furusho, Aya, Nishida, Norifumi, Ito, Sohei, Hayashi, Makiko, Yasukawa, Hideo, Imaizumi, Tsutomu, Hiromatsu, Sinichi, Tanaka, Hiroyuki, Fukumoto, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046542/
https://www.ncbi.nlm.nih.gov/pubmed/32140621
http://dx.doi.org/10.1016/j.jacbts.2019.10.010