Cargando…

The Protective Effect of Basic Fibroblast Growth Factor on Diabetic Nephropathy Through Remodeling Metabolic Phenotype and Suppressing Oxidative Stress in Mice

Diabetic nephropathy is a common complication in diabetes, but still lack of effective therapeutic strategies. This study aimed to investigate the therapeutic effect of basic fibroblast growth factor (bFGF) in db/db mice with diabetic nephropathy and explore its possible metabolic mechanisms using a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Tingting, Shu, Qi, Ning, Jie, Wang, Shuaijie, Li, Chen, Zhao, Liangcai, Zheng, Hong, Gao, Hongchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046551/ https://www.ncbi.nlm.nih.gov/pubmed/32153399 http://dx.doi.org/10.3389/fphar.2020.00066

Ejemplares similares

Cellular phenotypic transitions in diabetic nephropathy: An update
por: Cao, Yiling, et al.
Publicado: (2022)

Metabolic effects of basic fibroblast growth factor in streptozotocin-induced diabetic rats: A (1)H NMR-based metabolomics investigation
por: Lin, Xiaodong, et al.
Publicado: (2016)

Feedback Activation of Basic Fibroblast Growth Factor Signaling via the Wnt/β-Catenin Pathway in Skin Fibroblasts
por: Wang, Xu, et al.
Publicado: (2017)

Resveratrol Modulates the Gut Microbiota and Inflammation to Protect Against Diabetic Nephropathy in Mice
por: Cai, Ting-Ting, et al.
Publicado: (2020)

Metabonomic analysis of potential biomarkers and drug targets involved in diabetic nephropathy mice
por: Wei, Tingting, et al.
Publicado: (2015)

Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage
por: Li, Liu-Gen, et al.
Publicado: (2022)

Resveratrol Protects Against Post-Contrast Acute Kidney Injury in Rabbits With Diabetic Nephropathy
por: Wang, Yongfang, et al.
Publicado: (2019)

Astragalin Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis and in Human Fibroblast-Like Synoviocytes
por: Jia, Qingyun, et al.
Publicado: (2019)

Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43
por: Chen, Ying, et al.
Publicado: (2020)

Blockage of S100A8/A9 ameliorates septic nephropathy in mice
por: Shi, Wei, et al.
Publicado: (2023)

Neohesperidin Protects Angiotensin II-Induced Hypertension and Vascular Remodeling
por: Zhang, Jingsi, et al.
Publicado: (2022)

Protective effects and possible mechanisms of catalpol against diabetic nephropathy in animal models: a systematic review and meta-analysis
por: Fu, Zhongmei, et al.
Publicado: (2023)

TRAF6 Suppresses the Development of Pulmonary Fibrosis by Attenuating the Activation of Fibroblasts
por: Min, Jiali, et al.
Publicado: (2022)

Basic Fibroblast Growth Factor Attenuates Injury in Myocardial Infarction by Enhancing Hypoxia-Inducible Factor-1 Alpha Accumulation
por: Rao, Zhiheng, et al.
Publicado: (2020)

Novel Immunomodulatory Cytokine Regulates Inflammation, Diabetes, and Obesity to Protect From Diabetic Nephropathy
por: Sabapathy, Vikram, et al.
Publicado: (2019)

Suppressing NK Cells by Astragaloside IV Protects Against Acute Ischemic Stroke in Mice Via Inhibiting STAT3
por: Li, Shichun, et al.
Publicado: (2022)

Fibroblast Growth Factor 21 Modulates Microglial Polarization That Attenuates Neurodegeneration in Mice and Cellular Models of Parkinson's Disease
por: Yang, Changwei, et al.
Publicado: (2021)

Src Activation Aggravates Podocyte Injury in Diabetic Nephropathy via Suppression of FUNDC1-Mediated Mitophagy
por: Zheng, Ting, et al.
Publicado: (2022)

Heparanase-2 protein and peptides have a protective effect on experimental glomerulonephritis and diabetic nephropathy
por: Buijsers, Baranca, et al.
Publicado: (2023)

Dihydromyricetin Protects against Bone Loss in Ovariectomized Mice by Suppressing Osteoclast Activity
por: Zhao, Libo, et al.
Publicado: (2017)

Metformin Protects the Heart Against Hypertrophic and Apoptotic Remodeling After Myocardial Infarction
por: Loi, Halyna, et al.
Publicado: (2019)

Dipeptidyl peptidase 4 expression is not associated with an activated fibroblast phenotype in idiopathic pulmonary fibrosis
por: Kadefors, Måns, et al.
Publicado: (2022)

Red Blood Cell Membrane-Camouflaged PLGA Nanoparticles Loaded With Basic Fibroblast Growth Factor for Attenuating Sepsis-Induced Cardiac Injury
por: Li, Xinze, et al.
Publicado: (2022)

Targeting Gremlin 1 Prevents Intestinal Fibrosis Progression by Inhibiting the Fatty Acid Oxidation of Fibroblast Cells
por: Yang, Yang, et al.
Publicado: (2021)

Turbina oblongata Protects Against Oxidative Cardiotoxicity by Suppressing Lipid Dysmetabolism and Modulating Cardiometabolic Activities Linked to Cardiac Dysfunctions
por: Erukainure, Ochuko L., et al.
Publicado: (2021)

MYH9 Inhibition Suppresses TGF-β1-Stimulated Lung Fibroblast-to-Myofibroblast Differentiation
por: Sun, Xionghua, et al.
Publicado: (2021)

Thymoquinone protects the testes of hypothyroid rats by suppressing pro-inflammatory cytokines and oxidative stress and promoting SIRT1 testicular expression
por: Algaidi, Sami A., et al.
Publicado: (2022)

miR-133: A Suppressor of Cardiac Remodeling?
por: Li, Ning, et al.
Publicado: (2018)

Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis
por: Liu, Yi, et al.
Publicado: (2018)

Shensong Yangxin Protects Against Metabolic Syndrome-Induced Ventricular Arrhythmias by Inhibiting Electrical Remodeling
por: Yang, Hong-Jie, et al.
Publicado: (2020)

Jintiange Capsules Ameliorate Osteoarthritis by Modulating Subchondral Bone Remodeling and Protecting Cartilage Against Degradation
por: Zhuang, Chenyang, et al.
Publicado: (2021)

Using Recombinant Human Collagen With Basic Fibroblast Growth Factor to Provide a Simulated Extracellular Matrix Microenvironment for the Revascularization and Attachment of Islets to the Transplantation Region
por: Zhu, Qunyan, et al.
Publicado: (2020)

Efficacy of lenvatinib combined with sequential transarterial chemoembolization for primary hepatocellular carcinoma and the effects on serum basic fibroblast growth factor and vascular endothelial growth factor
por: Xie, Qing-Yun, et al.
Publicado: (2022)

Quercetin Attenuates Podocyte Apoptosis of Diabetic Nephropathy Through Targeting EGFR Signaling
por: Liu, Yiqi, et al.
Publicado: (2022)

Liposome-Encapsulated Baicalein Suppressed Lipogenesis and Extracellular Matrix Formation in Hs68 Human Dermal Fibroblasts
por: Fang, Chien-Liang, et al.
Publicado: (2018)

Metabolic-suppressed cancer-associated fibroblasts limit the immune environment and survival in colorectal cancer with liver metastasis
por: Wu, Chenghao, et al.
Publicado: (2023)

Yishen Huashi Granules Ameliorated the Development of Diabetic Nephropathy by Reducing the Damage of Glomerular Filtration Barrier
por: Zhao, Tingting, et al.
Publicado: (2022)

Herbal Medicine “Shulifenxiao” Formula for Nephrotic Syndrome of Refractory Idiopathic Membranous Nephropathy
por: Cui, Hailan, et al.
Publicado: (2021)

Qiliqiangxin Modulates the Gut Microbiota and NLRP3 Inflammasome to Protect Against Ventricular Remodeling in Heart Failure
por: Lu, Yingdong, et al.
Publicado: (2022)

BM-MSCs alleviate diabetic nephropathy in male rats by regulating ER stress, oxidative stress, inflammation, and apoptotic pathways
por: Khamis, Tarek, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ami1bpl5um3qvdao3ke4j8ppjd