Cargando…

HDAC6, modulated by miR-206, promotes endometrial cancer progression through the PTEN/AKT/mTOR pathway

Endometrial cancer (EC) is the sixth most common cancer in women. Since early EC has a good prognosis, identifying methods for early diagnosis is valuable. Here, we aimed to study the role of HDAC6, which has been indicated important in many kinds of cancers, in EC diagnosis and therapy. First, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Yawen, Yang, Xiaohui, Wang, Chunyan, Zhang, Shuo, Wang, Zhiling, Li, Meng, Wang, Yuanjian, Wang, Xiaojie, Yang, Xingsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046652/ https://www.ncbi.nlm.nih.gov/pubmed/32107418 http://dx.doi.org/10.1038/s41598-020-60271-4

Ejemplares similares

Dual inhibition of AKT‐mTOR and AR signaling by targeting HDAC3 in PTEN‐ or SPOP‐mutated prostate cancer
por: Yan, Yuqian, et al.
Publicado: (2018)

Inhibition of the AKT/mTOR pathway negatively regulates PTEN expression via miRNAs: Effect of Akt/mTOR inhibition on PTEN expression
por: Wan, Linyan, et al.
Publicado: (2022)

MAF1 suppresses AKT‐mTOR signaling and liver cancer through activation of PTEN transcription
por: Li, Yue, et al.
Publicado: (2016)

MicroRNA‐221 promotes breast cancer resistance to adriamycin via modulation of PTEN/Akt/mTOR signaling
por: Yin, Yingchun, et al.
Publicado: (2020)

YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas
por: Xu, Wei, et al.
Publicado: (2021)

Combinatorial antitumor effect of HDACs and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer
por: Ellis, Leigh, et al.
Publicado: (2013)

Oleic Acid Exhibits Anti-Proliferative and Anti-Invasive Activities via the PTEN/AKT/mTOR Pathway in Endometrial Cancer
por: Deng, Boer, et al.
Publicado: (2023)

Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway
por: Liang, Yu, et al.
Publicado: (2019)

Upregulated TRIM29 promotes proliferation and metastasis of nasopharyngeal carcinoma via PTEN/AKT/mTOR signal pathway
por: Zhou, Xiao-Min, et al.
Publicado: (2016)

E2F7−EZH2 axis regulates PTEN/AKT/mTOR signalling and glioblastoma progression
por: Yang, Rui, et al.
Publicado: (2020)

Aurora-A Induces Chemoresistance Through Activation of the AKT/mTOR Pathway in Endometrial Cancer
por: Wu, Jun, et al.
Publicado: (2019)

SPTBN2 regulated by miR-424-5p promotes endometrial cancer progression via CLDN4/PI3K/AKT axis
por: Wang, Pengling, et al.
Publicado: (2021)

Effect of mTOR Inhibitors in Nude Mice with Endometrial Carcinoma and Variable PTEN Expression Status
por: Fong, Pedro, et al.
Publicado: (2014)

PTEN/AKT/mTOR signaling mediates anticancer effects of epigallocatechin-3-gallate in ovarian cancer
por: Qin, Jianli, et al.
Publicado: (2020)

Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway
por: Li, Xiao-yu, et al.
Publicado: (2017)

Correction: SPTBN2 regulated by miR-424-5p promotes endometrial cancer progression via CLDN4/PI3K/AKT axis
por: Wang, Pengling, et al.
Publicado: (2022)

Chrysin induces autophagy through the inactivation of the ROS-mediated Akt/mTOR signaling pathway in endometrial cancer
por: He, Yu, et al.
Publicado: (2021)

MiR-206 regulates the progression of osteoporosis via targeting HDAC4
por: Lu, Zhiyuan, et al.
Publicado: (2021)

Shikonin suppresses proliferation and induces apoptosis in endometrioid endometrial cancer cells via modulating miR-106b/PTEN/AKT/mTOR signaling pathway
por: Huang, Caimei, et al.
Publicado: (2018)

Genetic Variations in a PTEN/AKT/mTOR Axis and Prostate Cancer Risk in a Chinese Population
por: Chen, Jiawei, et al.
Publicado: (2012)

Berberine Reverses Doxorubicin Resistance by Inhibiting Autophagy Through the PTEN/Akt/mTOR Signaling Pathway in Breast Cancer
por: Wang, Ye, et al.
Publicado: (2020)

Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling
por: Li, Li, et al.
Publicado: (2017)

MiR-146b inhibits autophagy in prostate cancer by targeting the PTEN/Akt/mTOR signaling pathway
por: Gao, Song, et al.
Publicado: (2018)

Xuesaitong Protects Podocytes from Apoptosis in Diabetic Rats through Modulating PTEN-PDK1-Akt-mTOR Pathway
por: Xue, Rui, et al.
Publicado: (2020)

Tripartite motif 27 promotes cardiac hypertrophy via PTEN/Akt/mTOR signal pathways
por: Chen, Yan, et al.
Publicado: (2022)

HDAC6 regulates primordial follicle activation through mTOR signaling pathway
por: Zhang, Tuo, et al.
Publicado: (2021)

miR-214 ameliorates sepsis-induced acute kidney injury via PTEN/AKT/mTOR-regulated autophagy
por: Sang, Zhenzhen, et al.
Publicado: (2021)

Feedback activation of STAT3 limits the response to PI3K/AKT/mTOR inhibitors in PTEN-deficient cancer cells
por: Wang, Jian, et al.
Publicado: (2021)

Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway
por: Xu, Maolin, et al.
Publicado: (2022)

Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1
por: Wang, Shiwen, et al.
Publicado: (2015)

Hsa_circ_0000199 facilitates chemo-tolerance of triple-negative breast cancer by interfering with miR-206/613-led PI3K/Akt/mTOR signaling
por: Li, Hongchang, et al.
Publicado: (2021)

Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway
por: Shi, Lungang, et al.
Publicado: (2019)

Cardioprotective Effect of Tangeretin by Inhibiting PTEN/AKT/mTOR Axis in Experimental Sepsis-Induced Myocardial Dysfunction
por: Shiroorkar, Predeepkumar Narayanappa, et al.
Publicado: (2020)

MicroRNA-206 exerts anti-oncogenic functions in esophageal squamous cell carcinoma by suppressing the c-Met/AKT/mTOR pathway
por: Zhang, Jin, et al.
Publicado: (2019)

Correction: MiR-146b inhibits autophagy in prostate cancer through affecting PTEN/AKT/mTOR signaling pathway
por: Gao, Song, et al.
Publicado: (2019)

Epithelial cell adhesion molecule overexpression regulates epithelial-mesenchymal transition, stemness and metastasis of nasopharyngeal carcinoma cells via the PTEN/AKT/mTOR pathway
por: Wang, Meng-He, et al.
Publicado: (2018)

The Paradox of Akt-mTOR Interactions
por: Vadlakonda, Lakshmipathi, et al.
Publicado: (2013)

HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling pathway
por: Yu, Lei, et al.
Publicado: (2023)

Tetrahydrofolate Alleviates the Inhibitory Effect of Oxidative Stress on Neural Stem Cell Proliferation through PTEN/Akt/mTOR Pathway
por: Zhang, Xuyang, et al.
Publicado: (2022)

Correction: Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1
por: Wang, Shiwen, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mn9negeak56fenkjtk6hvadeeb