Mosaic chromosome Y loss is associated with alterations in blood cell counts in UK Biobank men

Mosaic loss of Y chromosome (mLOY) is the most frequently detected somatic copy number alteration in leukocytes of men. In this study, we investigate blood cell counts as a potential mechanism linking mLOY to disease risk in 206,353 UK males. Associations between mLOY, detected by genotyping arrays,...

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Detalles Bibliográficos
Autores principales: Lin, Shu-Hong, Loftfield, Erikka, Sampson, Josh N., Zhou, Weiyin, Yeager, Meredith, Freedman, Neal D., Chanock, Stephen J., Machiela, Mitchell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046668/
https://www.ncbi.nlm.nih.gov/pubmed/32108144
http://dx.doi.org/10.1038/s41598-020-59963-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046668/
https://www.ncbi.nlm.nih.gov/pubmed/32108144
http://dx.doi.org/10.1038/s41598-020-59963-8

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