Multi-resolution localization of causal variants across the genome

In the statistical analysis of genome-wide association data, it is challenging to precisely localize the variants that affect complex traits, due to linkage disequilibrium, and to maximize power while limiting spurious findings. Here we report on KnockoffZoom: a flexible method that localizes causal...

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Detalles Bibliográficos
Autores principales: Sesia, Matteo, Katsevich, Eugene, Bates, Stephen, Candès, Emmanuel, Sabatti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046731/
https://www.ncbi.nlm.nih.gov/pubmed/32107378
http://dx.doi.org/10.1038/s41467-020-14791-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046731/
https://www.ncbi.nlm.nih.gov/pubmed/32107378
http://dx.doi.org/10.1038/s41467-020-14791-2

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