Cargando…
A toxin-antidote CRISPR gene drive system for regional population modification
Engineered gene drives based on a homing mechanism could rapidly spread genetic alterations through a population. However, such drives face a major obstacle in the form of resistance against the drive. In addition, they are expected to be highly invasive. Here, we introduce the Toxin-Antidote Recess...
Autores principales: | Champer, Jackson, Lee, Esther, Yang, Emily, Liu, Chen, Clark, Andrew G., Messer, Philipp W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046741/ https://www.ncbi.nlm.nih.gov/pubmed/32109227 http://dx.doi.org/10.1038/s41467-020-14960-3 |
Ejemplares similares
-
Performance analysis of novel toxin-antidote CRISPR gene drive systems
por: Champer, Jackson, et al.
Publicado: (2020) -
Design and analysis of CRISPR‐based underdominance toxin‐antidote gene drives
por: Champer, Jackson, et al.
Publicado: (2020) -
Assessment of distant-site rescue elements for CRISPR toxin-antidote gene drives
por: Chen, Jingheng, et al.
Publicado: (2023) -
Experimental demonstration of tethered gene drive systems for confined population modification or suppression
por: Metzloff, Matthew, et al.
Publicado: (2022) -
Molecular safeguarding of CRISPR gene drive experiments
por: Champer, Jackson, et al.
Publicado: (2019)