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Delivering Crocetin across the Blood-Brain Barrier by Using γ-Cyclodextrin to Treat Alzheimer’s Disease
Crocetin (CRT) has shown various neuroprotective effects such as antioxidant activities and the inhibition of amyloid β fibril formation, and thus is a potential therapeutic candidate for Alzheimer’s disease (AD). However, poor water solubility and bioavailability are the major obstacles in formulat...
Autores principales: | Wong, Ka Hong, Xie, Yuning, Huang, Xiao, Kadota, Kazunori, Yao, Xin-Sheng, Yu, Yang, Chen, Xiaoyu, Lu, Aiping, Yang, Zhijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046745/ https://www.ncbi.nlm.nih.gov/pubmed/32107408 http://dx.doi.org/10.1038/s41598-020-60293-y |
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