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Protein and DNA methylation-based scores as surrogate markers for interferon system activation in patients with primary Sjögren’s syndrome

OBJECTIVE: Standard assessment of interferon (IFN) system activity in systemic rheumatic diseases depends on the availability of RNA samples. In this study, we describe and evaluate alternative methods using plasma, serum and DNA samples, exemplified in the IFN-driven disease primary Sjögren’s syndr...

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Detalles Bibliográficos
Autores principales: Björk, Albin, Richardsdotter Andersson, Elina, Imgenberg-Kreuz, Juliana, Thorlacius, Gudny Ella, Mofors, Johannes, Syvänen, Ann-Christine, Kvarnström, Marika, Nordmark, Gunnel, Wahren-Herlenius, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046975/
https://www.ncbi.nlm.nih.gov/pubmed/31958277
http://dx.doi.org/10.1136/rmdopen-2019-000995