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Dataset of allele, genotype and haplotype frequencies of four polymorphisms filaggrin gene in Russian patients with atopic dermatitis

Data on the allele, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) (rs3126085, rs12144049, rs471144 and rs4363385) filaggrin (FLG) gene in Russian patients with atopic dermatitis are presented. Genome-wide association studies identified these SNPs could be signific...

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Detalles Bibliográficos
Autores principales: Belyaeva, Tatyana, Ponomarenko, Irina, Reshetnikov, Evgeny, Polonikov, Alexey, Aristova, Inna, Elykova, Anna, Rudykh, Natalya, Churnosov, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047013/
https://www.ncbi.nlm.nih.gov/pubmed/32140520
http://dx.doi.org/10.1016/j.dib.2020.105307
Descripción
Sumario:Data on the allele, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) (rs3126085, rs12144049, rs471144 and rs4363385) filaggrin (FLG) gene in Russian patients with atopic dermatitis are presented. Genome-wide association studies identified these SNPs could be significant genetic markers associated with atopic dermatitis. The frequencies of alleles, genotypes and haplotypes of four SNPs were calculated in 3 groups: entire sample, females and males. No significant differences in the allele, genotype and haplotype frequencies between males and females with AD patients were observed.