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Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series

BACKGROUND : Pathological studies have reported that patients with acute coronary syndrome (ACS) may have different plaque morphologies at culprit lesions, and one of the underlying mechanisms for ACS is plaque erosion. However, the morphological features of plaque erosion obtained by multiple intra...

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Autores principales: Yamaguchi, Masao, Sugiyama, Tomoyo, Hoshino, Masahiro, Kanaji, Yoshihisa, Hada, Masahiro, Usui, Eisuke, Yonetsu, Taishi, Kakuta, Tsunekazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047054/
https://www.ncbi.nlm.nih.gov/pubmed/32128487
http://dx.doi.org/10.1093/ehjcr/ytz241
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author Yamaguchi, Masao
Sugiyama, Tomoyo
Hoshino, Masahiro
Kanaji, Yoshihisa
Hada, Masahiro
Usui, Eisuke
Yonetsu, Taishi
Kakuta, Tsunekazu
author_facet Yamaguchi, Masao
Sugiyama, Tomoyo
Hoshino, Masahiro
Kanaji, Yoshihisa
Hada, Masahiro
Usui, Eisuke
Yonetsu, Taishi
Kakuta, Tsunekazu
author_sort Yamaguchi, Masao
collection PubMed
description BACKGROUND : Pathological studies have reported that patients with acute coronary syndrome (ACS) may have different plaque morphologies at culprit lesions, and one of the underlying mechanisms for ACS is plaque erosion. However, the morphological features of plaque erosion obtained by multiple intracoronary imaging modalities have not been fully elucidated. CASE SUMMARY : We experienced two cases with ACS of culprit lesions exhibiting optical coherence tomography (OCT)-defined plaque erosion. Additional examinations using near-infrared spectroscopy (NIRS)–intravascular ultrasound and coronary angioscopy suggested the presence of two distinct phenotypes of plaque erosion. These two types of erosion differ in the extent of NIRS-derived lipid core burden and coronary angioscopy-derived luminal surface colour. DISCUSSION : OCT-defined plaque erosion may not be the unique entity but have at least two distinct plaque morphologies, and NIRS and/or coronary angioscopy may provide incremental ability of discriminating these plaque phenotypes classified as plaque erosion by OCT.
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spelling pubmed-70470542020-03-03 Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series Yamaguchi, Masao Sugiyama, Tomoyo Hoshino, Masahiro Kanaji, Yoshihisa Hada, Masahiro Usui, Eisuke Yonetsu, Taishi Kakuta, Tsunekazu Eur Heart J Case Rep Case Series BACKGROUND : Pathological studies have reported that patients with acute coronary syndrome (ACS) may have different plaque morphologies at culprit lesions, and one of the underlying mechanisms for ACS is plaque erosion. However, the morphological features of plaque erosion obtained by multiple intracoronary imaging modalities have not been fully elucidated. CASE SUMMARY : We experienced two cases with ACS of culprit lesions exhibiting optical coherence tomography (OCT)-defined plaque erosion. Additional examinations using near-infrared spectroscopy (NIRS)–intravascular ultrasound and coronary angioscopy suggested the presence of two distinct phenotypes of plaque erosion. These two types of erosion differ in the extent of NIRS-derived lipid core burden and coronary angioscopy-derived luminal surface colour. DISCUSSION : OCT-defined plaque erosion may not be the unique entity but have at least two distinct plaque morphologies, and NIRS and/or coronary angioscopy may provide incremental ability of discriminating these plaque phenotypes classified as plaque erosion by OCT. Oxford University Press 2020-01-25 /pmc/articles/PMC7047054/ /pubmed/32128487 http://dx.doi.org/10.1093/ehjcr/ytz241 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Series
Yamaguchi, Masao
Sugiyama, Tomoyo
Hoshino, Masahiro
Kanaji, Yoshihisa
Hada, Masahiro
Usui, Eisuke
Yonetsu, Taishi
Kakuta, Tsunekazu
Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series
title Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series
title_full Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series
title_fullStr Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series
title_full_unstemmed Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series
title_short Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series
title_sort two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047054/
https://www.ncbi.nlm.nih.gov/pubmed/32128487
http://dx.doi.org/10.1093/ehjcr/ytz241
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