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Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series
BACKGROUND : Pathological studies have reported that patients with acute coronary syndrome (ACS) may have different plaque morphologies at culprit lesions, and one of the underlying mechanisms for ACS is plaque erosion. However, the morphological features of plaque erosion obtained by multiple intra...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047054/ https://www.ncbi.nlm.nih.gov/pubmed/32128487 http://dx.doi.org/10.1093/ehjcr/ytz241 |
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author | Yamaguchi, Masao Sugiyama, Tomoyo Hoshino, Masahiro Kanaji, Yoshihisa Hada, Masahiro Usui, Eisuke Yonetsu, Taishi Kakuta, Tsunekazu |
author_facet | Yamaguchi, Masao Sugiyama, Tomoyo Hoshino, Masahiro Kanaji, Yoshihisa Hada, Masahiro Usui, Eisuke Yonetsu, Taishi Kakuta, Tsunekazu |
author_sort | Yamaguchi, Masao |
collection | PubMed |
description | BACKGROUND : Pathological studies have reported that patients with acute coronary syndrome (ACS) may have different plaque morphologies at culprit lesions, and one of the underlying mechanisms for ACS is plaque erosion. However, the morphological features of plaque erosion obtained by multiple intracoronary imaging modalities have not been fully elucidated. CASE SUMMARY : We experienced two cases with ACS of culprit lesions exhibiting optical coherence tomography (OCT)-defined plaque erosion. Additional examinations using near-infrared spectroscopy (NIRS)–intravascular ultrasound and coronary angioscopy suggested the presence of two distinct phenotypes of plaque erosion. These two types of erosion differ in the extent of NIRS-derived lipid core burden and coronary angioscopy-derived luminal surface colour. DISCUSSION : OCT-defined plaque erosion may not be the unique entity but have at least two distinct plaque morphologies, and NIRS and/or coronary angioscopy may provide incremental ability of discriminating these plaque phenotypes classified as plaque erosion by OCT. |
format | Online Article Text |
id | pubmed-7047054 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-70470542020-03-03 Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series Yamaguchi, Masao Sugiyama, Tomoyo Hoshino, Masahiro Kanaji, Yoshihisa Hada, Masahiro Usui, Eisuke Yonetsu, Taishi Kakuta, Tsunekazu Eur Heart J Case Rep Case Series BACKGROUND : Pathological studies have reported that patients with acute coronary syndrome (ACS) may have different plaque morphologies at culprit lesions, and one of the underlying mechanisms for ACS is plaque erosion. However, the morphological features of plaque erosion obtained by multiple intracoronary imaging modalities have not been fully elucidated. CASE SUMMARY : We experienced two cases with ACS of culprit lesions exhibiting optical coherence tomography (OCT)-defined plaque erosion. Additional examinations using near-infrared spectroscopy (NIRS)–intravascular ultrasound and coronary angioscopy suggested the presence of two distinct phenotypes of plaque erosion. These two types of erosion differ in the extent of NIRS-derived lipid core burden and coronary angioscopy-derived luminal surface colour. DISCUSSION : OCT-defined plaque erosion may not be the unique entity but have at least two distinct plaque morphologies, and NIRS and/or coronary angioscopy may provide incremental ability of discriminating these plaque phenotypes classified as plaque erosion by OCT. Oxford University Press 2020-01-25 /pmc/articles/PMC7047054/ /pubmed/32128487 http://dx.doi.org/10.1093/ehjcr/ytz241 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Series Yamaguchi, Masao Sugiyama, Tomoyo Hoshino, Masahiro Kanaji, Yoshihisa Hada, Masahiro Usui, Eisuke Yonetsu, Taishi Kakuta, Tsunekazu Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series |
title | Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series |
title_full | Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series |
title_fullStr | Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series |
title_full_unstemmed | Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series |
title_short | Two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series |
title_sort | two distinct phenotypes of plaque erosion assessed by multimodality intracoronary imaging: a case series |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047054/ https://www.ncbi.nlm.nih.gov/pubmed/32128487 http://dx.doi.org/10.1093/ehjcr/ytz241 |
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