IL-10 Protects Mice From the Lung Infection of Acinetobacter baumannii and Contributes to Bacterial Clearance by Regulating STAT3-Mediated MARCO Expression in Macrophages

Interleukin-10 plays important, yet contrasting, roles in host protection against bacterial infections and in the septic response. To determine the role of IL-10 in the host defense against Acinetobacter baumannii infection, wild-type (WT) and IL-10-deficient mice were infected intranasally with the...

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Detalles Bibliográficos
Autores principales: Kang, Min-Jung, Jang, Ah-Ra, Park, Ji-Yeon, Ahn, Jae-Hun, Lee, Tae-Sung, Kim, Dong-Yeon, Lee, Moo-Seung, Hwang, Seungwoo, Jeong, Yu-Jin, Park, Jong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047127/
https://www.ncbi.nlm.nih.gov/pubmed/32153580
http://dx.doi.org/10.3389/fimmu.2020.00270

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