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Brozopine Inhibits 15-LOX-2 Metabolism Pathway After Transient Focal Cerebral Ischemia in Rats and OGD/R-Induced Hypoxia Injury in PC12 Cells

The goal of this study was to elucidate the mechanisms of protection of Sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate (trade name: Brozopine, BZP) against cerebral ischemia in vivo and in vitro. To explore the protective effect of BZP on focal cerebral ischemia-reperfusion injury, we evaluated the...

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Detalles Bibliográficos
Autores principales:	Gao, Yuan, Cao, Xinyu, Zhang, Xiaojiao, Wang, Yangjun, Huang, He, Meng, Yonggang, Chang, Junbiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047151/ https://www.ncbi.nlm.nih.gov/pubmed/32153408 http://dx.doi.org/10.3389/fphar.2020.00099

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