Systematic identification of CDC34 that functions to stabilize EGFR and promote lung carcinogenesis

BACKGROUND: How the oncoprotein epidermal growth factor receptor (EGFR) evades proteolytic degradation and accumulates in non-small cell lung cancer (NSCLC) remains unclear, and ubiquitin pathway genes (UPGs) that are critical to NSCLC needs to be systematically identified. METHODS: A total of 696 U...

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Detalles Bibliográficos
Autores principales: Zhao, Xin-Chun, Wang, Gui-Zhen, Wen, Zhe-Sheng, Zhou, Yong-Chun, Hu, Qian, Zhang, Bin, Qu, Li-Wei, Gao, San-Hui, Liu, Jie, Ma, Liang, Zhang, Yan-Fei, Zhang, Chen, Yu, Hong, Zhang, Da-Lin, Wang, Min, Wang, Chang-Li, Huang, Yun-Chao, Liu, Zhi-hua, Zhao, Yong, Chen, Liang, Zhou, Guang-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047192/
https://www.ncbi.nlm.nih.gov/pubmed/32114396
http://dx.doi.org/10.1016/j.ebiom.2020.102689

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