L-Ascorbic Acid and α-Tocopherol Synergistically Triggers Apoptosis Inducing Antileukemic Effects of Arsenic Trioxide via Oxidative Stress in Human Acute Promyelocytic Leukemia Cells

Chemosensitization is an effective strategy to overcome the drawbacks of arsenic trioxide (As(2)O(3)) treatment, which may be possible through the use of dietary supplements in combination. The present investigation evaluates the synergistic mechanism of action of vitamins, such as L-ascorbic acid (...

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Detalles Bibliográficos
Autores principales: Vineetha, Radhakrishnan Chandraprabha, Hariharan, Sreedharan, Jaleel, Abdul, Chandran, Mahesh, Nair, Raveendran Harikumaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047343/
https://www.ncbi.nlm.nih.gov/pubmed/32154163
http://dx.doi.org/10.3389/fonc.2020.00065

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