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Remission of autoimmune diabetes by anti-TCR combination therapies with anti-IL-17A or/and anti-IL-6 in the IDDM rat model of type 1 diabetes

BACKGROUND: The cytokine IL-17 is a key player in autoimmune processes, while the cytokine IL-6 is responsible for the chronification of inflammation. However, their roles in type 1 diabetes development are still unknown. METHODS: Therefore, therapies for 5 days with anti-IL-17A or anti-IL-6 in comb...

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Detalles Bibliográficos
Autores principales:	Jörns, Anne, Ishikawa, Daichi, Teraoku, Hiroki, Yoshimoto, Toshiaki, Wedekind, Dirk, Lenzen, Sigurd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047363/ https://www.ncbi.nlm.nih.gov/pubmed/32106855 http://dx.doi.org/10.1186/s12916-020-1503-6

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