A novel miR-0308-3p revealed by miRNA-seq of HBV-positive hepatocellular carcinoma suppresses cell proliferation and promotes G1/S arrest by targeting double CDK6/Cyclin D1 genes

BACKGROUND: Persistent infection with hepatitis B virus (HBV) accounts for the majority of hepatocellular carcinoma (HCC), but the molecular mechanisms underlying liver carcinogenesis are still not completely understood. Increasing evidence demonstrates that microRNAs (miRNAs) play significant funct...

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Detalles Bibliográficos
Autores principales: Dai, Xiaoming, Huang, Ruixue, Hu, Sai, Zhou, Yao, Sun, Xiaoya, Gui, Pucheng, Yu, Zijian, Zhou, Pingkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047384/
https://www.ncbi.nlm.nih.gov/pubmed/32128112
http://dx.doi.org/10.1186/s13578-020-00382-7

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