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Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond

Ubiquitin (UB) transfer cascades consisting of E1, E2, and E3 enzymes constitute a complex network that regulates a myriad of biologic processes by modifying protein substrates. Deubiquitinating enzymes (DUBs) reverse UB modifications or trim UB chains of diverse linkages. Additionally, many cellula...

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Detalles Bibliográficos
Autores principales:	Zhao, Bo, Tsai, Yien Che, Jin, Bo, Wang, Bufan, Wang, Yiyang, Zhou, Han, Carpenter, Tomaya, Weissman, Allan M., Yin, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Pharmacology and Experimental Therapeutics 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047443/ https://www.ncbi.nlm.nih.gov/pubmed/32107274 http://dx.doi.org/10.1124/pr.118.015651

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