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The use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: A retrospective analysis of a novel technique

BACKGROUND AND AIMS: Liposomal bupivacaine (LB) is a formulation of local anesthetic that may exert analgesia over a prolonged period. Anecdotal use of LB suggests benefit and prolonged analgesia when used to supplement infiltration blocks. Our aim was to test the effect of a bolus of LB delivered t...

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Autores principales: Elsharkawy, Hesham, Saasouh, Wael, Cho, Yoon Jeong, Soliman, Loran Mounir, Horn, Jean-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047671/
https://www.ncbi.nlm.nih.gov/pubmed/32174670
http://dx.doi.org/10.4103/joacp.JOACP_358_18
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author Elsharkawy, Hesham
Saasouh, Wael
Cho, Yoon Jeong
Soliman, Loran Mounir
Horn, Jean-Louis
author_facet Elsharkawy, Hesham
Saasouh, Wael
Cho, Yoon Jeong
Soliman, Loran Mounir
Horn, Jean-Louis
author_sort Elsharkawy, Hesham
collection PubMed
description BACKGROUND AND AIMS: Liposomal bupivacaine (LB) is a formulation of local anesthetic that may exert analgesia over a prolonged period. Anecdotal use of LB suggests benefit and prolonged analgesia when used to supplement infiltration blocks. Our aim was to test the effect of a bolus of LB delivered through a nerve catheter in two types of interfascial plane blocks (transversus abdominis plane and anterior subcostal quadratus lumborum). The effect was evaluated through patient self-reporting of postsurgical pain up to 48 postoperative hours. MATERIAL AND METHODS: Medical records of adult postoperative patients who received LB in a peripheral nerve catheter were followed retrospectively and analysed for pain scores and spread of dermatomal numbness over 48 h following the postoperative dose. A chart review of patients who qualified between June 2015 and March 2017 was performed, and clinical data were obtained from the institutional Perioperative Health Documentation System. RESULTS: Pain scores decreased following LB bolus, and all patients reported efficient block analgesia after bolus injection. Dermatomal numbness decreased gradually and was minimal by 48 h following bolus. CONCLUSION: LB can be injected through a peripheral nerve catheter to prolong analgesia after catheter removal.
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spelling pubmed-70476712020-03-13 The use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: A retrospective analysis of a novel technique Elsharkawy, Hesham Saasouh, Wael Cho, Yoon Jeong Soliman, Loran Mounir Horn, Jean-Louis J Anaesthesiol Clin Pharmacol Clinical Pharmacology BACKGROUND AND AIMS: Liposomal bupivacaine (LB) is a formulation of local anesthetic that may exert analgesia over a prolonged period. Anecdotal use of LB suggests benefit and prolonged analgesia when used to supplement infiltration blocks. Our aim was to test the effect of a bolus of LB delivered through a nerve catheter in two types of interfascial plane blocks (transversus abdominis plane and anterior subcostal quadratus lumborum). The effect was evaluated through patient self-reporting of postsurgical pain up to 48 postoperative hours. MATERIAL AND METHODS: Medical records of adult postoperative patients who received LB in a peripheral nerve catheter were followed retrospectively and analysed for pain scores and spread of dermatomal numbness over 48 h following the postoperative dose. A chart review of patients who qualified between June 2015 and March 2017 was performed, and clinical data were obtained from the institutional Perioperative Health Documentation System. RESULTS: Pain scores decreased following LB bolus, and all patients reported efficient block analgesia after bolus injection. Dermatomal numbness decreased gradually and was minimal by 48 h following bolus. CONCLUSION: LB can be injected through a peripheral nerve catheter to prolong analgesia after catheter removal. Wolters Kluwer - Medknow 2020 2020-02-18 /pmc/articles/PMC7047671/ /pubmed/32174670 http://dx.doi.org/10.4103/joacp.JOACP_358_18 Text en Copyright: © 2020 Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Clinical Pharmacology
Elsharkawy, Hesham
Saasouh, Wael
Cho, Yoon Jeong
Soliman, Loran Mounir
Horn, Jean-Louis
The use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: A retrospective analysis of a novel technique
title The use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: A retrospective analysis of a novel technique
title_full The use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: A retrospective analysis of a novel technique
title_fullStr The use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: A retrospective analysis of a novel technique
title_full_unstemmed The use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: A retrospective analysis of a novel technique
title_short The use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: A retrospective analysis of a novel technique
title_sort use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: a retrospective analysis of a novel technique
topic Clinical Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047671/
https://www.ncbi.nlm.nih.gov/pubmed/32174670
http://dx.doi.org/10.4103/joacp.JOACP_358_18
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