Cargando…

Postoperative urinary retention: A controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine

BACKGROUND AND AIMS: Following spinal anesthesia (SA), patient discharge is often delayed due to postoperative urinary retention (POUR), the incidence of which varies widely. The present study of bupivacaine versus ropivacaine in equianalgesic doses was taken to explore the correlation between time...

Descripción completa

Detalles Bibliográficos
Autores principales: Haleem, Shahla, Ozair, Ahmad, Singh, Abhishek, Hasan, Muazzam, Athar, Manazir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047698/
https://www.ncbi.nlm.nih.gov/pubmed/32174666
http://dx.doi.org/10.4103/joacp.JOACP_221_18
_version_ 1783502167267606528
author Haleem, Shahla
Ozair, Ahmad
Singh, Abhishek
Hasan, Muazzam
Athar, Manazir
author_facet Haleem, Shahla
Ozair, Ahmad
Singh, Abhishek
Hasan, Muazzam
Athar, Manazir
author_sort Haleem, Shahla
collection PubMed
description BACKGROUND AND AIMS: Following spinal anesthesia (SA), patient discharge is often delayed due to postoperative urinary retention (POUR), the incidence of which varies widely. The present study of bupivacaine versus ropivacaine in equianalgesic doses was taken to explore the correlation between time to void urine and time for complete functional recovery. MATERIAL AND METHODS: In this double-blinded study fifty adult patients were assigned to two groups (bupivacaine/ropivacaine) according to alternate case allocation for receiving SA for lower abdominal, perineal, and lower limb surgeries, lasting less than 2 h. Statistical analysis was conducted using an intention-to-treat approach, using Mann–Whitney test for nonparametric data. Primary outcome data could not be obtained for 14 out of the 50 patients due to perioperative bladder catheterization. No patients were lost to follow-up. RESULTS: Both the bupivacaine and ropivacaine groups were comparable in terms of ability to void (8.0 ± 2.3 vs. 7.0 ± 1.2 h; P > 0.05), modified Bromage scale after 4 h of SA (1.8 ± 1.3 vs. 2.6 ± 0.9 grade; P > 0.05), time to complete ambulation (6.7 ± 1.4 vs. 6.1 ± 1.0 h; P > 0.05), and time to negative Romberg test (6.1 ± 1.4 vs. 5.6 ± 0.9 h; P > 0.05), respectively. Strong positive correlations (r = 0.7–0.9) were found between time to void urine and time for complete ambulation. CONCLUSIONS: Time to void urine and recovery of motor functions were found comparable statistically when bupivacaine and ropivacaine were used in the doses of 12.5 and 18.75 mg, respectively, for SA. However, group ropivacaine required lesser time to void and no patient developed POUR. Time to void urine was more than the time for ambulation. This may indicate a need for “selective spinal anesthesia” or adjuvant combination technique to accelerate the resolution of a block for ambulatory surgery.
format Online
Article
Text
id pubmed-7047698
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-70476982020-03-13 Postoperative urinary retention: A controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine Haleem, Shahla Ozair, Ahmad Singh, Abhishek Hasan, Muazzam Athar, Manazir J Anaesthesiol Clin Pharmacol Original Article BACKGROUND AND AIMS: Following spinal anesthesia (SA), patient discharge is often delayed due to postoperative urinary retention (POUR), the incidence of which varies widely. The present study of bupivacaine versus ropivacaine in equianalgesic doses was taken to explore the correlation between time to void urine and time for complete functional recovery. MATERIAL AND METHODS: In this double-blinded study fifty adult patients were assigned to two groups (bupivacaine/ropivacaine) according to alternate case allocation for receiving SA for lower abdominal, perineal, and lower limb surgeries, lasting less than 2 h. Statistical analysis was conducted using an intention-to-treat approach, using Mann–Whitney test for nonparametric data. Primary outcome data could not be obtained for 14 out of the 50 patients due to perioperative bladder catheterization. No patients were lost to follow-up. RESULTS: Both the bupivacaine and ropivacaine groups were comparable in terms of ability to void (8.0 ± 2.3 vs. 7.0 ± 1.2 h; P > 0.05), modified Bromage scale after 4 h of SA (1.8 ± 1.3 vs. 2.6 ± 0.9 grade; P > 0.05), time to complete ambulation (6.7 ± 1.4 vs. 6.1 ± 1.0 h; P > 0.05), and time to negative Romberg test (6.1 ± 1.4 vs. 5.6 ± 0.9 h; P > 0.05), respectively. Strong positive correlations (r = 0.7–0.9) were found between time to void urine and time for complete ambulation. CONCLUSIONS: Time to void urine and recovery of motor functions were found comparable statistically when bupivacaine and ropivacaine were used in the doses of 12.5 and 18.75 mg, respectively, for SA. However, group ropivacaine required lesser time to void and no patient developed POUR. Time to void urine was more than the time for ambulation. This may indicate a need for “selective spinal anesthesia” or adjuvant combination technique to accelerate the resolution of a block for ambulatory surgery. Wolters Kluwer - Medknow 2020 2020-02-18 /pmc/articles/PMC7047698/ /pubmed/32174666 http://dx.doi.org/10.4103/joacp.JOACP_221_18 Text en Copyright: © 2020 Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Haleem, Shahla
Ozair, Ahmad
Singh, Abhishek
Hasan, Muazzam
Athar, Manazir
Postoperative urinary retention: A controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine
title Postoperative urinary retention: A controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine
title_full Postoperative urinary retention: A controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine
title_fullStr Postoperative urinary retention: A controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine
title_full_unstemmed Postoperative urinary retention: A controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine
title_short Postoperative urinary retention: A controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine
title_sort postoperative urinary retention: a controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047698/
https://www.ncbi.nlm.nih.gov/pubmed/32174666
http://dx.doi.org/10.4103/joacp.JOACP_221_18
work_keys_str_mv AT haleemshahla postoperativeurinaryretentionacontrolledtrialoffixeddosespinalanesthesiausingbupivacaineversusropivacaine
AT ozairahmad postoperativeurinaryretentionacontrolledtrialoffixeddosespinalanesthesiausingbupivacaineversusropivacaine
AT singhabhishek postoperativeurinaryretentionacontrolledtrialoffixeddosespinalanesthesiausingbupivacaineversusropivacaine
AT hasanmuazzam postoperativeurinaryretentionacontrolledtrialoffixeddosespinalanesthesiausingbupivacaineversusropivacaine
AT atharmanazir postoperativeurinaryretentionacontrolledtrialoffixeddosespinalanesthesiausingbupivacaineversusropivacaine