Identification of Anti-Mycobacterium and Anti-Legionella Compounds With Potential Distinctive Structural Scaffolds From an HD-PBL Using Phenotypic Screens in Amoebae Host Models

Tubercular Mycobacteria and Legionella pneumophila are the causative agents of potentially fatal respiratory diseases due to their intrinsic pathogenesis but also due to the emergence of antibiotic resistance that limits treatment options. The aim of our study was to explore the antimicrobial activi...

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Detalles Bibliográficos
Autores principales: Hanna, Nabil, Kicka, Sébastien, Chiriano, Gianpaolo, Harrison, Christopher, Sakouhi, Hajer Ouertatani, Trofimov, Valentin, Kranjc, Agata, Nitschke, Jahn, Pagni, Marco, Cosson, Pierre, Hilbi, Hubert, Scapozza, Leonardo, Soldati, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047896/
https://www.ncbi.nlm.nih.gov/pubmed/32153546
http://dx.doi.org/10.3389/fmicb.2020.00266

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