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Incidence of ROS1-Rearranged Non-Small-Cell Lung Carcinoma in India and Efficacy of Crizotinib in Lung Adenocarcinoma Patients

BACKGROUND: The ROS1 gene is a member of the “sevenless” subfamily of tyrosine-kinase insulin-receptor genes. ROS1-fusion rearrangement causes constitutive downstream signal transduction, with an oncogenic role in non-small-cell lung carcinoma (NSCLC). Fortunately, crizotinib, an ALK1 tyrosine-kinas...

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Detalles Bibliográficos
Autores principales:	Mehta, Anurag, Saifi, Mumtaz, Batra, Ullas, Suryavanshi, M, Gupta, Kush
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047993/ https://www.ncbi.nlm.nih.gov/pubmed/32158297 http://dx.doi.org/10.2147/LCTT.S244366

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