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The in vivo role of Rev1 in mutagenesis and carcinogenesis

Translesion synthesis (TLS) is an error-prone pathway required to overcome replication blockage by DNA damage. Aberrant activation of TLS has been suggested to play a role in tumorigenesis by promoting genetic mutations. However, the precise molecular mechanisms underlying TLS-mediated tumorigenesis...

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Detalles Bibliográficos
Autores principales:	Sasatani, Megumi, Zaharieva, Elena Karamfilova, Kamiya, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048032/ https://www.ncbi.nlm.nih.gov/pubmed/32161626 http://dx.doi.org/10.1186/s41021-020-0148-1

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