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Takotsubo cardiomyopathy in cancer patients
BACKGROUND: Cancer is a chronic condition that induces significant emotional and physical stress, which may increase the risk for developing Takotsubo cardiomyopathy (TCM). MAIN BODY: Takotsubo cardiomyopathy, also known as stress cardiomyopathy, is a clinical syndrome that generally presents as che...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048040/ https://www.ncbi.nlm.nih.gov/pubmed/32154014 http://dx.doi.org/10.1186/s40959-019-0042-9 |
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author | Desai, Aakash Noor, Arish Joshi, Saurabh Kim, Agnes S. |
author_facet | Desai, Aakash Noor, Arish Joshi, Saurabh Kim, Agnes S. |
author_sort | Desai, Aakash |
collection | PubMed |
description | BACKGROUND: Cancer is a chronic condition that induces significant emotional and physical stress, which may increase the risk for developing Takotsubo cardiomyopathy (TCM). MAIN BODY: Takotsubo cardiomyopathy, also known as stress cardiomyopathy, is a clinical syndrome that generally presents as chest pain mimicking acute coronary syndrome or as an acute heart failure characterized by severe left ventricular systolic dysfunction in response to emotional, physical, or medical stress. The potential triggers for Takotsubo syndrome in cancer patients include the emotional turmoil of a cancer diagnosis, the inflammatory state of the cancer itself, and the physical stress of cancer surgery, systemic anti-neoplastic therapy, and radiation treatment. TCM is becoming increasingly recognized among patients with cancer and has been associated with adverse outcomes in this patient population. In this study, we searched the Pubmed database using keywords “Takotsubo cardiomyopathy”, “cancer”, and “anti-neoplastic therapy” to review case reports of Takotsubo syndrome occurring in oncologic patients after systemic anti-neoplastic therapy. Clinical presentation, electrocardiogram, laboratory data, transthoracic echocardiogram and coronary angiogram results, and patient outcomes were collected and analyzed. CONCLUSION: Patients with cancer are at an elevated risk for developing stress cardiomyopathy, and it is important to know which cancer drugs have been associated with the development of the Takotsubo syndrome. |
format | Online Article Text |
id | pubmed-7048040 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-70480402020-03-09 Takotsubo cardiomyopathy in cancer patients Desai, Aakash Noor, Arish Joshi, Saurabh Kim, Agnes S. Cardiooncology Review BACKGROUND: Cancer is a chronic condition that induces significant emotional and physical stress, which may increase the risk for developing Takotsubo cardiomyopathy (TCM). MAIN BODY: Takotsubo cardiomyopathy, also known as stress cardiomyopathy, is a clinical syndrome that generally presents as chest pain mimicking acute coronary syndrome or as an acute heart failure characterized by severe left ventricular systolic dysfunction in response to emotional, physical, or medical stress. The potential triggers for Takotsubo syndrome in cancer patients include the emotional turmoil of a cancer diagnosis, the inflammatory state of the cancer itself, and the physical stress of cancer surgery, systemic anti-neoplastic therapy, and radiation treatment. TCM is becoming increasingly recognized among patients with cancer and has been associated with adverse outcomes in this patient population. In this study, we searched the Pubmed database using keywords “Takotsubo cardiomyopathy”, “cancer”, and “anti-neoplastic therapy” to review case reports of Takotsubo syndrome occurring in oncologic patients after systemic anti-neoplastic therapy. Clinical presentation, electrocardiogram, laboratory data, transthoracic echocardiogram and coronary angiogram results, and patient outcomes were collected and analyzed. CONCLUSION: Patients with cancer are at an elevated risk for developing stress cardiomyopathy, and it is important to know which cancer drugs have been associated with the development of the Takotsubo syndrome. BioMed Central 2019-07-01 /pmc/articles/PMC7048040/ /pubmed/32154014 http://dx.doi.org/10.1186/s40959-019-0042-9 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Desai, Aakash Noor, Arish Joshi, Saurabh Kim, Agnes S. Takotsubo cardiomyopathy in cancer patients |
title | Takotsubo cardiomyopathy in cancer patients |
title_full | Takotsubo cardiomyopathy in cancer patients |
title_fullStr | Takotsubo cardiomyopathy in cancer patients |
title_full_unstemmed | Takotsubo cardiomyopathy in cancer patients |
title_short | Takotsubo cardiomyopathy in cancer patients |
title_sort | takotsubo cardiomyopathy in cancer patients |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048040/ https://www.ncbi.nlm.nih.gov/pubmed/32154014 http://dx.doi.org/10.1186/s40959-019-0042-9 |
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