Effects of dexrazoxane on doxorubicin-related cardiotoxicity and second malignant neoplasms in children with osteosarcoma: a report from the Children’s Oncology Group

BACKGROUND: Dexrazoxane protects from lower-cumulative-dose doxorubicin cardiotoxicity, but the effect of dexrazoxane in children with sarcoma treated with higher-cumulative-dose doxorubicin is unknown. METHODS: We evaluated children with osteosarcoma (OS) on two Children’s Oncology Group trials wit...

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Detalles Bibliográficos
Autores principales: Kopp, Lisa M., Womer, Richard B., Schwartz, Cindy L., Ebb, David H., Franco, Vivian I., Hall, David, Barkauskas, Donald A., Krailo, Mark D., Grier, Holcombe E., Meyers, Paul A., Wexler, Leonard H., Marina, Neyssa M., Janeway, Katherine A., Gorlick, Richard, Bernstein, Mark L., Lipshultz, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048050/
https://www.ncbi.nlm.nih.gov/pubmed/32154021
http://dx.doi.org/10.1186/s40959-019-0050-9

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