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Evaluation of surrogacy in the multi-trial setting based on information theory: an extension to ordinal outcomes
Summary: In clinical trials, surrogate outcomes are early measures of treatment effect that are used to predict treatment effect on a later primary outcome of interest: the primary outcome therefore does not need to be observed and trials can be shortened. Evaluating surrogates is a complex area as...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048082/ https://www.ncbi.nlm.nih.gov/pubmed/31887069 http://dx.doi.org/10.1080/10543406.2019.1696357 |