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Clinical use of Capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids
The skin is the largest organ in the human body; beyond its regulatory and sensory roles, it is meant to protect and act like a barrier against foreign matter. Products intended to restore the skin health should reintegrate the structure of the stratum corneum in which the corneocytes are surrounded...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioExcel Publishing Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048133/ https://www.ncbi.nlm.nih.gov/pubmed/32158486 http://dx.doi.org/10.7573/dic.2019-10-1 |
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author | Giacomelli, Luca Moglia, Alessandra Losa, Gianedoardo Quaglino, Pietro |
author_facet | Giacomelli, Luca Moglia, Alessandra Losa, Gianedoardo Quaglino, Pietro |
author_sort | Giacomelli, Luca |
collection | PubMed |
description | The skin is the largest organ in the human body; beyond its regulatory and sensory roles, it is meant to protect and act like a barrier against foreign matter. Products intended to restore the skin health should reintegrate the structure of the stratum corneum in which the corneocytes are surrounded by the intercellular lipid lamellae that maintain both corneum integrity and skin permeability barrier. Capilen is a specific liposomal formulation based on a technology through which highly concentrated fresh plant extracts are conveyed into a jelly-like liposomal vehicle and combined with plant-derived omega-3, -6, -7, and -9 fatty acids, phospholipids, and precursors of ceramides. Its components have been widely investigated and produced clinical benefits in atopic dermatitis, bedsores, scars, inflammatory lesions of the skin, and generally whenever signs of xerosis cutis were present. Liposomes contribute to restore the surface lipid layer of the skin and to deliver substances in the activity site. This liposomal cream was proven to limit and delay the occurrence of radiodermatitis in breast cancer patients, and as an add-on provided complete healing of bedsore lesions in geriatric subjects. |
format | Online Article Text |
id | pubmed-7048133 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioExcel Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-70481332020-03-10 Clinical use of Capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids Giacomelli, Luca Moglia, Alessandra Losa, Gianedoardo Quaglino, Pietro Drugs Context Review The skin is the largest organ in the human body; beyond its regulatory and sensory roles, it is meant to protect and act like a barrier against foreign matter. Products intended to restore the skin health should reintegrate the structure of the stratum corneum in which the corneocytes are surrounded by the intercellular lipid lamellae that maintain both corneum integrity and skin permeability barrier. Capilen is a specific liposomal formulation based on a technology through which highly concentrated fresh plant extracts are conveyed into a jelly-like liposomal vehicle and combined with plant-derived omega-3, -6, -7, and -9 fatty acids, phospholipids, and precursors of ceramides. Its components have been widely investigated and produced clinical benefits in atopic dermatitis, bedsores, scars, inflammatory lesions of the skin, and generally whenever signs of xerosis cutis were present. Liposomes contribute to restore the surface lipid layer of the skin and to deliver substances in the activity site. This liposomal cream was proven to limit and delay the occurrence of radiodermatitis in breast cancer patients, and as an add-on provided complete healing of bedsore lesions in geriatric subjects. BioExcel Publishing Ltd 2020-01-09 /pmc/articles/PMC7048133/ /pubmed/32158486 http://dx.doi.org/10.7573/dic.2019-10-1 Text en Copyright © 2020 Giacomelli L, Moglia A, Losa G, Quaglino P. Published by Drugs in Context under Creative Commons License Deed CC BY NC ND 4.0 which allows anyone to copy, distribute, and transmit the article provided it is properly attributed in the manner specified below. No commercial use without permission. |
spellingShingle | Review Giacomelli, Luca Moglia, Alessandra Losa, Gianedoardo Quaglino, Pietro Clinical use of Capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids |
title | Clinical use of Capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids |
title_full | Clinical use of Capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids |
title_fullStr | Clinical use of Capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids |
title_full_unstemmed | Clinical use of Capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids |
title_short | Clinical use of Capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids |
title_sort | clinical use of capilen, a liposomal cream based on fresh plant extracts enriched with omega fatty acids |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048133/ https://www.ncbi.nlm.nih.gov/pubmed/32158486 http://dx.doi.org/10.7573/dic.2019-10-1 |
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