A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers

BACKGROUND: TgDCX is a doublecortin-domain protein associated with the conoid fibers, a set of strongly curved non-tubular tubulin-polymers in Toxoplasma. TgDCX deletion impairs conoid structure and parasite invasion. TgDCX contains two tubulin-binding domains: a partial P25α and the DCX/doublecorti...

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Detalles Bibliográficos
Autores principales: Leung, Jacqueline M., Nagayasu, Eiji, Hwang, Yu-Chen, Liu, Jun, Pierce, Phillip G., Phan, Isabelle Q., Prentice, Robin A., Murray, John M., Hu, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048138/
https://www.ncbi.nlm.nih.gov/pubmed/32111164
http://dx.doi.org/10.1186/s12860-020-0249-5

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