Pregabalin induced visual hallucinations – a rare adverse reaction

BACKGROUND: Pregabalin is an anticonvulsive, analgesic and anxiolytic medication. The typical side effects include dizziness, somnolence and weight gain. Few studies or case reports have demonstrated psychiatric side effects resulting from its use. CASE PRESENTATION: We present a patient who suffere...

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Autores principales: Mousailidis, Georgios, Papanna, Basavaraja, Salmon, Andrew, Sein, Aung, Al-Hillawi, Qutaiba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048142/
https://www.ncbi.nlm.nih.gov/pubmed/32111255
http://dx.doi.org/10.1186/s40360-020-0395-6
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author Mousailidis, Georgios
Papanna, Basavaraja
Salmon, Andrew
Sein, Aung
Al-Hillawi, Qutaiba
author_facet Mousailidis, Georgios
Papanna, Basavaraja
Salmon, Andrew
Sein, Aung
Al-Hillawi, Qutaiba
author_sort Mousailidis, Georgios
collection PubMed
description BACKGROUND: Pregabalin is an anticonvulsive, analgesic and anxiolytic medication. The typical side effects include dizziness, somnolence and weight gain. Few studies or case reports have demonstrated psychiatric side effects resulting from its use. CASE PRESENTATION: We present a patient who suffered visual hallucinations and agitation associated with an increase in pregabalin dose, resolving completely after pregabalin discontinuation. CONCLUSIONS: Acute visual hallucinations should be considered in the clinical spectrum of very rare side effects of pregabalin use, especially at higher doses. Tapered discontinuation of the medication can improve and resolve symptoms.
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spelling pubmed-70481422020-03-05 Pregabalin induced visual hallucinations – a rare adverse reaction Mousailidis, Georgios Papanna, Basavaraja Salmon, Andrew Sein, Aung Al-Hillawi, Qutaiba BMC Pharmacol Toxicol Case Report BACKGROUND: Pregabalin is an anticonvulsive, analgesic and anxiolytic medication. The typical side effects include dizziness, somnolence and weight gain. Few studies or case reports have demonstrated psychiatric side effects resulting from its use. CASE PRESENTATION: We present a patient who suffered visual hallucinations and agitation associated with an increase in pregabalin dose, resolving completely after pregabalin discontinuation. CONCLUSIONS: Acute visual hallucinations should be considered in the clinical spectrum of very rare side effects of pregabalin use, especially at higher doses. Tapered discontinuation of the medication can improve and resolve symptoms. BioMed Central 2020-02-28 /pmc/articles/PMC7048142/ /pubmed/32111255 http://dx.doi.org/10.1186/s40360-020-0395-6 Text en © The Author(s). 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Mousailidis, Georgios
Papanna, Basavaraja
Salmon, Andrew
Sein, Aung
Al-Hillawi, Qutaiba
Pregabalin induced visual hallucinations – a rare adverse reaction
title Pregabalin induced visual hallucinations – a rare adverse reaction
title_full Pregabalin induced visual hallucinations – a rare adverse reaction
title_fullStr Pregabalin induced visual hallucinations – a rare adverse reaction
title_full_unstemmed Pregabalin induced visual hallucinations – a rare adverse reaction
title_short Pregabalin induced visual hallucinations – a rare adverse reaction
title_sort pregabalin induced visual hallucinations – a rare adverse reaction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048142/
https://www.ncbi.nlm.nih.gov/pubmed/32111255
http://dx.doi.org/10.1186/s40360-020-0395-6
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