7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors

A series of 3H-1,2-benzoxathiepine 2,2-dioxides incorporating 7-acylamino moieties were obtained by an original procedure starting from 5-nitrosalicylaldehyde, which was treated with propenylsulfonyl chloride followed by Wittig reaction of the bis-olefin intermediate. The new derivatives, belonging...

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Detalles Bibliográficos
Autores principales: Pustenko, Aleksandrs, Nocentini, Alessio, Balašova, Anastasija, Krasavin, Mikhail, Žalubovskis, Raivis, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048192/
https://www.ncbi.nlm.nih.gov/pubmed/32079427
http://dx.doi.org/10.1080/14756366.2020.1722658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048192/
https://www.ncbi.nlm.nih.gov/pubmed/32079427
http://dx.doi.org/10.1080/14756366.2020.1722658

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