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miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension

The microRNA miR-1 is an important regulator of muscle phenotype including cardiac muscle. Down-regulation of miR-1 has been shown to occur in left ventricular hypertrophy but its contribution to right ventricular hypertrophy in pulmonary arterial hypertension are not known. Previous studies have su...

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Detalles Bibliográficos
Autores principales:	Connolly, Martin, Garfield, Benjamin E., Crosby, Alexi, Morrell, Nick W., Wort, Stephen J., Kemp, Paul R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048278/ https://www.ncbi.nlm.nih.gov/pubmed/32109943 http://dx.doi.org/10.1371/journal.pone.0229409

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